Medicina China HoyTraditional Chinese Medicine
Medicinal herb · Heat Clearing

Dì Gǔ Pí · Wolfberry Root Bark

Dì Gǔ Pí (地骨皮, Wolfberry Root Bark) is a herb of Cold nature and Sweet flavor, in the “Heat Clearing” category. Tradition uses it to cool the heat of deficiency in blood and bones, Clear Lung heat and stop cough, Cool blood and stop bleeding.

地骨皮 · Dì Gǔ PíUpdated on

Energetic profile

Pinyin name
Dì Gǔ Pí
Characters
地骨皮
Botanical name
Lycium chinense Mill.
Family
Solanaceae
Part used
Root bark
Nature
Cold
Flavor
Sweet
Meridians
Lung, Liver, Kidney
Category
Heat Clearing
Toxicity
Non-toxic
Pregnancy
No contraindication described (always consult)
Origin
China, Japan, Korea

Actions according to tradition

  • Cool the heat of deficiency in blood and bones
  • Clear Lung heat and stop cough
  • Cool blood and stop bleeding

Traditional uses

  • Evening fever and night sweats due to Yin deficiency (bone heat)
  • Cough due to heat of the Lung with bloody sputum
  • Hemoptysis, epistaxis and metrorrhagia due to heat in the blood
  • Diabetes (Xiao Ke) with chronic low fever
  • Heat-sensitive teeth from Kidney deficiency

Studied effects and current applications

  • Eliminate deep empty heat (bone fever, evening fever, night sweats)
  • Clears the heat of the Lung and stops coughing with yellow sputum
  • Cools blood in heat bleeds
  • Hipoglucemiante moderado
  • mild hypotensive

Applications under investigation

  • Menopause with hot flashes and night sweats
  • Tuberculosis pulmonar
  • Mild hypertension
  • Diabetes mellitus
  • Anemia with deficiency fever

An effect being investigated does not mean it has been proven in humans.

Contraindications and adverse effects

Absolute contraindications

  • Cold-damp pattern without heat of Yin deficiency
  • Spleen deficiency with diarrhea due to cold

Relative contraindications

  • arterial hypotension
  • Diabetes (monitorizar glucemia)
Pregnancy
Use with caution. Cold nature must be monitored.
Breastfeeding
Generally safe during breastfeeding.
Children
Safe for children with deficiency fever.
Older adults
Useful for elderly people with hot flashes and night sweats. Combine with warm spleen herbs.

Possible adverse effects

  • Diarrhea due to cold nature
  • Hypotension

When to stop

  • Diarrhea appears
  • Hypotension
  • Cold pattern worsens

Interactions with medications

GroupDrugsSeverityEffect and recommendation
Hypoglycemic agentsInsulin, MetforminModerateSignificant additive hypoglycemic effect Monitorizar glucemia de cerca.
AntihypertensivesBeta-blockers, IECAMildAdditive hypotensive effect Monitor blood pressure.

With other herbs

  • zhi_mu Synergistic to clear deficiency heat (bone heat)

Reference dose

Decoction
6-12 g daily
Powder
2-4 g daily
Acute use
1-2 weeks
Chronic use
1-2 months
Maximum
Long-term use with caution
Children
Safe for children with Yin deficiency fever.

Forms of preparation

Decoction

Boil 6-12g in 3 cups of water for 30 min. Drink lukewarm to cool depending on the pattern.

Evening fever, bone heat, Yin deficiency

Powder

Take 2-4g in warm water.

Convenience, mild chronic use

Approximate doses from the literature; they are not a prescription. Consult a professional.

Active compounds

Alkaloids (kukoamine) and phenolics (catechins, chlorogenic acid)

Kukoamine and kukoamine A

Polyamine alkaloids · Antihypertensive, anti-inflammatory, antioxidant

ACE inhibition, L-type calcium channel blockade · 0.1-0.8% in bark

Betaine and nicotine

simple alkaloids · Hepatoprotective, antipyretic

Methyl group donor, thermoregulation modulation · 0.05-0.2%

Catechins and chlorogenic acid

Polyphenols · Antioxidant, antidiabetic, anti-inflammatory

AMPK activation, α-glucosidase inhibition · 1-3%

Scopoletin and coumarin

Coumarins · Antipyretic, anti-inflammatory

Prostaglandin inhibition, thermoregulation modulation · 0.01-0.1%

Harvesting and processing

Harvest
spring and autumn

Root bark collected from 3+ year old plants. The bark is removed and dried in the sun. The bark of Lycium chinense (枸杞根皮) is the authentic one.

Raw (地骨皮 Dì Gǔ Pí)

Root bark cleaned, cut into strips and dried in the sun.

Health notice. Educational and study content. It describes concepts of Traditional Chinese Medicine and does not replace diagnosis or treatment by a healthcare professional. Needling, medicinal herbs and invasive techniques must be applied by trained professionals. Safety guide.