Medicina China HoyTraditional Chinese Medicine
Medicinal herb · Yang Tonifying

Tú Sī Zǐ · Chinese Dodder Seed

Tú Sī Zǐ (菟丝子, Chinese Dodder Seed) is a herb of Neutral nature and Sweet, Pungent flavor, in the “Yang Tonifying” category. Tradition uses it to tonify Kidney Yang and Yin, Secure Essence, Calm Fetus.

菟丝子 · Tú Sī ZǐUpdated on

Energetic profile

Pinyin name
Tú Sī Zǐ
Characters
菟丝子
Botanical name
Cuscuta chinensis Lam.
Family
Convolvulaceae
Part used
Seed
Nature
Neutral
Flavor
Sweet, Pungent
Meridians
Kidney, Liver, Spleen
Category
Yang Tonifying
Toxicity
Non-toxic
Pregnancy
No contraindication described (always consult)
Origin
China

Actions according to tradition

  • Tonify Kidney Yang and Yin
  • Secure Essence
  • Calm Fetus
  • Brighten Eyes

Traditional uses

  • Kidney deficiency with impotence and nocturnal emissions
  • Frequent urination and incontinence
  • Threatened miscarriage from kidney deficiency
  • Blurry vision and eye disorders from deficiency
  • Spleen-kidney deficiency diarrhea

Studied effects and current applications

  • Tonifies kidney yang and yin simultaneously (neutral herb)
  • Secures kidney essence to stop leakage
  • Stabilizes and calms restless fetus
  • Brightens eyes and vision from liver-kidney nourishment
  • Strengthens spleen to stop diarrhea

Applications under investigation

  • Male reproductive disorders and infertility
  • Recurrent miscarriage
  • Osteoporosis prevention
  • Vision deterioration from aging
  • Thyroid conditions

An effect being investigated does not mean it has been proven in humans.

Contraindications and adverse effects

Absolute contraindications

  • Kidney fire from yin deficiency (excess heat signs)
  • Constipation from heat

Relative contraindications

  • Excess heat conditions
Pregnancy
Often used in pregnancy to secure kidney essence and prevent miscarriage.
Breastfeeding
Safe during breastfeeding.
Children
Not generally used in children.
Older adults
Excellent tonic for elderly with kidney deficiency. Neutral temperature is gentle.

Possible adverse effects

  • Rare: mild dryness with excess use

When to stop

  • Kidney fire signs appear
  • Constipation develops

Interactions with medications

GroupDrugsSeverityEffect and recommendation
Hormone medicationsTestosterone, DHEA, ProgesteroneMildMay complement hormonal effects Monitor hormone levels

Reference dose

Decoction
6-12 grams daily
Powder
3-6 grams daily
Acute use
2-4 weeks
Chronic use
1-3 months
Maximum
Continuous long-term for chronic kidney deficiency
Children
Generally not used in children.

Forms of preparation

Decoction

Simmer 6-12g in 3 cups water 30-40 min. Take warm twice daily.

Kidney deficiency, reproductive disorders

Pills

Traditional form: take 6-12g equivalent as pills with salt water.

Long-term tonification

Approximate doses from the literature; they are not a prescription. Consult a professional.

Active compounds

Flavonoids (kaempferol, quercetin glycosides) and polysaccharides

Kaempferol and kaempferitrin

Flavonol and flavonol diglucoside · Phytoestrogenic, neuroprotective, antioxidant, renoprotective

Estrogen receptor β binding, Nrf2 activation, MAPK inhibition · 0.1-0.5%

Hypericin (trace) and amentoflavone

Anthraquinone and biflavonoid · Mild antidepressant, antiviral

MAO-A inhibition (hypericin), viral replication inhibition (amentoflavone) · Traces

Cuscuta Polysaccharides (CPS)

Heterogeneous polysaccharides · Immunomodulator, hepatoprotective, hypoglycemic

Macrophage activation, hepatocytes protection, α-glucosidase inhibition · 10-20% in aqueous extract

Resinols (cuscutin, hyperoside)

Lignans and flavonoids · Adaptogenic, anti-fatigue

HPA axis modulation, cortisol reduction · 0.05-0.2%

Harvesting and processing

Harvest
Autumn (September-October) when the seeds are ripe

Seeds collected when the dry parasitic stem separates from the host. The seeds are threshed and cleaned and dried in the sun.

Raw (生菟丝子 Shēng Tú Sī Zǐ)

Seeds cleaned, sifted and dried in the sun. The hard testa reduces the absorption of active ingredients in decoction.

Fried with salt (盐菟丝子 Yán Tú Sī Zǐ)

Seeds mixed with salt water (2 g salt per 100 g) and fried until they burst. The salt directs the action towards the Kidney and the high temperatures break the testa to improve absorption.

Formulas it appears in

Health notice. Educational and study content. It describes concepts of Traditional Chinese Medicine and does not replace diagnosis or treatment by a healthcare professional. Needling, medicinal herbs and invasive techniques must be applied by trained professionals. Safety guide.