Medicina China HoyTraditional Chinese Medicine
Medicinal herb · Dampness Draining

Yì Yǐ Rén · Coix Seed

Yì Yǐ Rén (薏苡仁, Coix Seed) is a herb of Cool nature and Sweet, BLAND flavor, in the “Dampness Draining” category. Tradition uses it to drain Dampness, Strengthen Spleen, Clear Heat.

薏苡仁 · Yì Yǐ RénUpdated on

Energetic profile

Pinyin name
Yì Yǐ Rén
Characters
薏苡仁
Botanical name
Coix lacryma-jobi var. ma-yuen (Rom.Caill.) Stapf
Family
Poaceae
Part used
Seed
Nature
Cool
Flavor
Sweet, BLAND
Meridians
Lung, Spleen, Stomach
Category
Dampness Draining
Toxicity
Non-toxic
Pregnancy
Avoid
Origin
China, Southeast Asia

Actions according to tradition

  • Drain Dampness
  • Strengthen Spleen
  • Clear Heat
  • Expel Pus

Traditional uses

  • Spleen deficiency with dampness causing diarrhea
  • Edema and difficult urination
  • Wind-damp arthritis and joint pain
  • Lung abscess and appendicitis
  • Skin conditions from damp-heat

Studied effects and current applications

  • Gently drains dampness and promotes urination
  • Strengthens spleen to improve digestion
  • Clears heat and relieves diarrhea
  • Expels pus and reduces swelling in abscesses
  • Treats wind-damp Bi syndrome (joint pain)

Applications under investigation

  • Arthritis and joint inflammation
  • Urinary tract conditions
  • Immune modulation
  • Skin disorders (warts, acne)
  • Anti-tumor adjunct therapy

An effect being investigated does not mean it has been proven in humans.

Contraindications and adverse effects

Absolute contraindications

  • Pregnancy (large doses)
  • Yin deficiency dry conditions without dampness

Relative contraindications

  • First trimester pregnancy (avoid large medicinal doses)
Pregnancy
Large medicinal doses may stimulate uterine contraction. Small culinary amounts may be acceptable after first trimester.
Breastfeeding
Safe as food herb during breastfeeding.
Children
Excellent as food herb for children with damp patterns.
Older adults
Excellent for elderly with damp-related conditions and joint pain.

Possible adverse effects

  • Rare: mild digestive upset

When to stop

  • During pregnancy (medicinal doses)
  • If dry conditions worsen

Interactions with medications

GroupDrugsSeverityEffect and recommendation
ChemotherapyVarious, PaclitaxelMildMay have synergistic anti-tumor effects (research ongoing) Inform oncologist

Reference dose

Decoction
9-30 grams daily
Powder
3-9 grams daily
Culinary use
30-60g as porridge or soup
Acute use
2-4 weeks
Chronic use
Months as food-herb
Maximum
Long-term as food is safe
Children
Safe for children. Excellent as food-herb porridge.

Forms of preparation

Decoction

Simmer 9-30g in 4 cups water 45 min.

Edema, joint pain, damp-heat

Porridge

Cook 30-60g with rice and water until soft. Eat as breakfast.

Spleen support, damp patterns, long-term use

Soup

Add to vegetable or bone broth soups, cook 1-2 hours.

Culinary use, family digestion support

Approximate doses from the literature; they are not a prescription. Consult a professional.

Active compounds

Polysaccharides (coixanes), coixenolide and fatty acids

Coixenolide (butyl tetradecyl hexadecanoate)

Polyacetylene/aliphatic ester · Antitumor, immunomodulatory, anti-inflammatory

Tumor apoptosis induction, NK cell activation, angiogenesis inhibition · 0.5-1.5% in lipid extract

Coixanes A, B, C (coixanpolysaccharides)

Hetrogeneous polysaccharides · Hypoglycemic, immunomodulatory

AMPK activation, B lymphocyte and macrophage stimulation · 5-20% in aqueous extract

Palmitic, stearic and oleic acid

fatty acids · General lipid components, coixenolide precursors

Integration into cell membranes, fluidity modulation · 3-8% in seed

Coixol (6-methoxybenzoxazolinone)

Benzoxazolinone · Antipyretic, analgesic, muscle relaxant

GABA-A modulation, Na+ channel blocking · 0.05-0.2%

Harvesting and processing

Harvest
Autumn (September-October) when the grains are fully ripe

Grains harvested when they are fully ripe and hard. The ears are threshed to separate the grains, the outer shells are removed and they are dried in the sun.

Raw (生薏苡仁 Shēng Yì Yǐ Rén)

Clean grains without outer shell, washed and dried in the sun. Standard form used in medicine.

Fried (炒薏苡仁 Chǎo Yì Yǐ Rén)

Dry fried grains over medium heat until lightly golden and fragrant. Toasting reduces coldness and enhances the toning action of the Spleen.

Formulas it appears in

Health notice. Educational and study content. It describes concepts of Traditional Chinese Medicine and does not replace diagnosis or treatment by a healthcare professional. Needling, medicinal herbs and invasive techniques must be applied by trained professionals. Safety guide.