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Medicinal herb · Blood Tonifying

Shú Dì Huáng · Prepared Rehmannia Root

Shú Dì Huáng (熟地黄, Prepared Rehmannia Root) is a herb of Warm nature and Sweet flavor, in the “Blood Tonifying” category. Tradition uses it to nourish Blood, Nourish Yin of Liver and Kidney, Tonify Essence.

熟地黄 · Shú Dì HuángUpdated on

Energetic profile

Pinyin name
Shú Dì Huáng
Characters
熟地黄
Botanical name
Rehmannia glutinosa (Gaertn.) DC.
Family
Orobanchaceae
Part used
Root (steamed with wine)
Nature
Warm
Flavor
Sweet
Meridians
Kidney, Liver
Category
Blood Tonifying
Toxicity
Non-toxic
Pregnancy
No contraindication described (always consult)
Origin
China

Actions according to tradition

  • Nourish Blood
  • Nourish Yin of Liver and Kidney
  • Tonify Essence
  • Fill Marrow

Traditional uses

  • Blood deficiency with pale complexion and heart palpitations
  • Liver and kidney yin deficiency
  • Dizziness, tinnitus, weakness in lumbar region
  • Night sweats and afternoon fever from yin deficiency
  • Premature graying of hair

Studied effects and current applications

  • Profoundly nourishes blood and yin
  • Strengthens kidney essence and bone marrow
  • Addresses premature aging signs (gray hair, weak knees)
  • Moistens dryness and alleviates thirst
  • Consolidates essence to prevent seminal loss

Applications under investigation

  • Anemia and blood disorders
  • Adrenal fatigue and burnout
  • Osteoporosis and bone deficiency
  • Menopausal syndrome
  • Male reproductive deficiency

An effect being investigated does not mean it has been proven in humans.

Contraindications and adverse effects

Absolute contraindications

  • Severe digestive weakness with abdominal distension
  • Phlegm-damp obstructing spleen

Relative contraindications

  • Spleen and stomach weakness
  • Use without digestive herbs (chen pi, sha ren)
Pregnancy
Generally considered safe; often used in pregnancy blood deficiency formulas.
Breastfeeding
Safe for nursing mothers.
Children
Use cautiously in children with weak digestion.
Older adults
Excellent for elderly blood and yin deficiency; use with digestive herbs to prevent stagnation.

Possible adverse effects

  • Abdominal fullness and bloating
  • Loose stools
  • Nausea if not combined with aromatic herbs

When to stop

  • Persistent digestive discomfort
  • Diarrhea develops

Interactions with medications

GroupDrugsSeverityEffect and recommendation
Diabetes medicationsMetformin, InsulinMildMay have mild hypoglycemic effect Monitor blood glucose
AnticoagulantsWarfarinMildMay slightly affect clotting Monitor INR

With other herbs

  • chen_pi Chen Pi helps prevent digestive stagnation from Shu Di Huang

Reference dose

Decoction
9-30 grams daily
Powder
3-9 grams daily
Acute use
2-4 weeks
Chronic use
1-3 months
Maximum
Continuous long-term possible in yin deficiency
Children
Use cautiously in children with digestive weakness.

Forms of preparation

Decoction

Simmer 9-30g in 4 cups water 45-60 min. Drink warm in two doses.

Maximum blood and yin tonification

Wine extraction

Steep in rice wine 2-4 weeks. Take 1-2 tsp daily.

Blood tonification and circulation

Approximate doses from the literature; they are not a prescription. Consult a professional.

Active compounds

Reduced iridoid glycosides, polysaccharides and verbascoside

Rehmanioside D and 5-HMF (5-hydroxymethylfurfural)

Modified iridoid glycoside and furan · Kidney tonic, antioxidant, hematopoietic

Generated during processing (steamed with wine); erythropoiesis stimulation, radical scavenging · Increased vs. Sheng Di Huang

Verbascoside (actoside)

Phenylpropanoid glucoside · Antioxidant, anti-inflammatory, neuroprotective

Radical scavenging, PKC inhibition, NF-κB inhibition · 0.1-0.5% (reduced after processing vs. raw form)

Processed Rehmannia Polysaccharides (PRPS)

Heterogeneous polysaccharides · Immunomodulator, hypoglycemic

Macrophage activation, α-glucosidase inhibition · 20-35% in aqueous extract

Ursolic acid and betulinic acid

Pentacyclic triterpenes · Anti-inflammatory, antitumor

NF-κB inhibition, mitochondrial apoptosis induction · Traces

Harvesting and processing

Harvest
Autumn (October-November) for raw Rehmannia base

Raw Rehmannia (生地黄) is harvested in autumn and then undergoes the process of nine steamings to become processed Rehmannia (熟地黄). This months-long process is the most elaborate in Chinese pharmacology.

Processed 9 times (熟地黄 Shú Dì Huáng)

COMPLEX PROCESS: Cleaned raw roots are mixed with yellow rice wine (30%), ginger juice and other herbs. They are subjected to repeated cycles of: vaporization 4-6 hours, cooling, sun exposure, vaporization. The classic minimum process is 9 cycles (九蒸九晒). The result is black, sweet and shiny.

Formulas it appears in

Health notice. Educational and study content. It describes concepts of Traditional Chinese Medicine and does not replace diagnosis or treatment by a healthcare professional. Needling, medicinal herbs and invasive techniques must be applied by trained professionals. Safety guide.